Continuous gluconic acid production by Aureobasidium pullulans with and without biomass retention

Abbreviations: Conversion (%): [(g consumed glucose/g feeding glucose) x 100], dilution of medium glucose by NaOH feeding was considered in the calculations mp: Specific gluconic acid productivity, [g gluconic acid/(g biomass x h)], Rj [g/(l x h)]/biomass concentration (g/l), g/(g x h) Rj: Formation rate of the generic product (volumetric productivity), g gluconic acid/(l x h), gluconic acid concentration (g/l)/RT (h), g/(l x h) Rs: Glucose consumption rate, g/(l x h), [(g feeding glucose-g consumed glucose)/RT (h)], g/(l x h) RT: Residence time hours, [Bioreactor volume (ml)/(medium feeding rate (ml/h) + NaOH feeding rate (ml/h))], h Selectivity (%): [(g gluconic acid/g consumed glucose) x 100] Yield (%): [(g gluconic acid/g feeding glucose) x 100]